New results from ultrafast spectroscopy and in-depth theoretical calculations demonstrate that the complex folded structure of tRNA is stabilized by magnesium ions in direct contact with phosphate ...

the P site positions the peptidyl-tRNA and the E site is occupied by all deacylated tRNAs before they dissociate from the ribosome. Figure 1: An overview of ribosomal structure and mRNA translation.

They make specific changes or additions to the tRNA structure, which enhance the efficiency and accuracy of the ...

those ribonucleosides usually undergo dozens of chemical modifications that alter the tRNA structure and function. A few years ago, Thomas Begley, a former MIT postdoctoral associate who is now an ...

New results from ultrafast spectroscopy and in-depth theoretical calculations demonstrate that the complex folded structure of tRNA is stabilized by magnesium ions in direct contact with phosphate ...

They make specific changes or additions to the tRNA structure, which enhance the efficiency and accuracy of the protein-building process. This ensures that the tRNA trucks are optimised and ...

The structure of a key enzyme involved in protein production is revealed by cryo-electron microscopy (cryo-EM). Using cryo-EM, researchers at Goethe University (Frankfurt, Germany) shed light on ...

tRNA strands twist into a 3D structure that from a certain angle looks like the state of Florida. When the tRNA’s southern tip, called its anticodon, pairs with the corresponding codon on mRNA ...

RNA breaks destined for repair are inflicted by sequence-specific or structure-specific endoribonucleases during physiological RNA processing (e.g. tRNA splicing; kinetoplast mRNA editing) and under ...

In translation, aa-tRNA, EF-Tu and GTP form a ternary complex that binds to the ribosome, allowing codon-anticodon pairing in the 30S ribosomal subunit. Cognate codon recognition triggers fast GTP ...

New results from ultrafast spectroscopy and in-depth theoretical calculations demonstrate that the complex folded structure of tRNA is stabilized by magnesium ions in direct contact with phosphate ...