Among the major classes of RNAs in the cell, tRNAs remain the most difficult to characterize via deep sequencing approaches, as tRNA structure and nucleotide modifications can each interfere with cDNA ...

tRNA therapy could potentially help to counteract the effects ... alterations in the DNA that results in a different amino acid being incorporated into the structure of a protein. In 2023, the company ...

Royalty-free licenses let you pay once to use copyrighted images and video clips in personal and commercial projects on an ongoing basis without requiring additional payments each time you use that ...

a Gold-standard 0.143 FSC resolution calculated with 3DFSC (Tan et al, 2017). The masks for FSC calculation were generated in CryoSPARC using a relative threshold of 0.5. b Gold-standard 0.143 FSC ...

The findings reveal how the absence of TRMT10A leads to a reduction in specific transfer RNA (tRNA) levels, disrupting protein synthesis in the brain and impairing synaptic structure and function.

Archaeosine is a modified nucleoside found only in the tRNAs from archaea, the so-called third domain of life, and contributes to the maintenance of the L-shaped tRNA three-dimensional structure.

They make specific changes or additions to the tRNA structure, which enhance the efficiency and accuracy of the protein-building process. This ensures that the tRNA trucks are optimised and tailored ...

They make specific changes or additions to the tRNA structure, which enhance the efficiency and accuracy of the protein-building process. This ensures that the tRNA trucks are optimized and ...

They make specific changes or additions to the tRNA structure, which enhance the efficiency and accuracy of the protein-building process. This ensures that the tRNA trucks are optimised and ...

This small RNA fragment disrupts mitochondrial protein synthesis and cristae structure, accelerating cognitive decline and Alzheimer’s pathology. By targeting these tRNA fragments with antisense ...