In the microscopic world of bacteria, gene transfer is a powerful mechanism that can alter cellular function, drive antibiotic resistance and even shape entire ecosystems.

In the microscopic world of bacteria, gene transfer is a powerful mechanism that can alter cellular function, drive ...

Single-molecule biophysics is the study of the dynamics and interactions of individual biomolecules to understand how they carry out their functions in living cells. For example, monitoring the ...

But a team of researchers led by Kishore Guda, associate professor at the Digestive Health Research Institute at the Case Western Reserve School of Medicine, found a special class of ribonucleic acid ...

Just like barcodes on products in a supermarket, which designate every individual type of item in the store, the unique DNA barcodes allow the researchers to tag each type of molecule in the sample.

The result is a three-dimensional Fourier, or electron-density, map of the unit cell, which for the first time reveals the general nature of the tertiary structure of a protein molecule.

Rare disease day is observed on 28 February. Credit: nambitomo via Getty Images. US-based biotechnology company Alltrna is developing transfer RNA (tRNA)-based therapies that aim to offer a broad ...

Takeda has returned to BridGene Biosciences for another small-molecule collaboration—this time focused on immunology as well as neurology. BridGene’s pursuit of undruggable targets is enabled ...

meaning that a tRNA sequence pairs with its complementary sequence on the mRNA molecule to make sure the correct amino acid is added to the chain as a protein is being built. Using yeast as a study ...

meaning that a tRNA sequence pairs with its complementary sequence on the mRNA molecule to make sure the correct amino acid is added to the chain as a protein is being built. Using yeast as a ...

The presentation entitled “Targeting the tRNA methyltransferase METTL1 with small molecule inhibitors in cancer” illustrates STORM’s new data showing that pharmacological inhibition of a tRNA ...

G-quadruplexes (G4s) are stable non-canonical secondary structures formed by G-rich DNA or RNA sequences. They play various regulatory roles in many biological processes. It is commonly agreed that G4 ...