Hairy-cell leukemia (HCL) is a rare, indolent neoplasm of mature B cells with hairlike surface projections that circulate in the blood and preferentially infiltrate the bone marrow and spleen.

Treatments for Dupuytren’s contracture include limited fasciectomy and collagenase injection. Comparisons of the effectiveness of these treatments have been limited. We performed an unblinded ...

Cerebral adrenoleukodystrophy is a severe form of X-linked adrenoleukodystrophy characterized by white-matter disease, loss of neurologic function, and early death. Elivaldogene autotemcel (eli ...

New data show that the United States continues to fall short when it comes to both protecting the health of individual people and promoting societal well-being. From the Harvard T.H. Chan School ...

Gene therapy with elivaldogene autotemcel (eli-cel) consisting of autologous CD34+ cells transduced with lentiviral vector containing ABCD1 complementary DNA (Lenti-D ...

More than 30 years ago, the first transplantation with autologous hematopoietic stem cells modified with integrated murine retroviral vectors carrying potentially therapeutic genes was performed ...

Dr. Danielle C. Crabtree (Medicine): A 37-year-old man was admitted to this hospital because of fever, myalgia, jaundice, and hypoxemia. The patient had been healthy until 9 days before this ...

From the Center for Latino Adolescent and Family Health (V.G.-R., M.T.-K., A.B.), and the Institute for Policy Solutions, School of Nursing (V.G.-R., M.T.-K., A.B ...

A 25-year-old woman receiving daily prednisolone treatment for systemic lupus erythematosus presented with a 3-month history of erosive, violaceous plaques in the antecubital fossae, popliteal ...

In this randomized trial, conducted between 1989 and 2022 to compare radical prostatectomy with watchful waiting, radical prostatectomy led to a 48% lower risk of death from prostate cancer and to ...

To the Editor: In their article on the DREAMM-7 trial, Hungria and colleagues (Aug. 1 issue) 1 describe the treatment of patients with multiple myeloma that had progressed after at least one line ...