Background Subcutaneous (SC) administration is the preferred parenteral opioid route in palliative care, while intravenous infusion may allow faster titration. Comparative evidence remains limited.

Objectives Pancreatic and lung cancer are associated with cancer cachexia (CC), which negatively impacts patients’ quality of life, treatment outcomes and prognosis. This study aimed to evaluate the ...

The Terminally Ill Adults (End of Life) Bill is currently under debate within the UK Parliament. If passed, the bill will affect individuals living in England and Wales, providing a legal framework ...

Most people die when they are old, but predicting exactly when this will occur is unavoidably uncertain. The health of older people is challenged by multimorbidity, disability and frailty. Frailty is ...

Background Virtual reality (VR) technology as a therapeutic intervention has been gaining attention in healthcare settings in recent years. Studies suggest that using the technology can help alleviate ...

Context Methadone is a useful option in the treatment of cancer pain. Despite its advantages, methadone use is complicated due to high interindividual variability in pharmacokinetics. Various rotation ...

Home-based oncology palliative care is racing against time. In Florence, Italy—a city with approximately 364 073 inhabitants in 2024, with 990 527 in its metropolitan area1—a resolute team of four ...

Objectives To examine whether use of a hand-held fan (‘fan’) improves breathlessness and increases physical activity. Methods A secondary exploratory analysis using pooled data from the fan arms of ...

Hyperpolarisation-activated cyclic nucleotide-gated (HCN) channels control neuronal firing thresholds. Together with sodium channels, they accumulate at sites of nerve injury, creating ectopic foci of ...

Objectives There have been many models of providing oncology and palliative care to hospitals. Many patients will use the hospital non-electively or semielectively, and a large proportion are likely ...

Objectives Supportive and palliative care include non-oncology settings where patients suffer from pain and quality of life-related concerns. Integrative medicine plays important roles in supportive ...

Background Palliative care (PC) education has become a priority in many European countries where PC is quickly developing. There remains, however, a lack of information on acceptability and medical ...