Scientists at UCL and the MRC Laboratory of Molecular Biology have recreated how RNA might have first replicated itself on ...

In 2012, scientists Jennifer Doudna and Emmanuelle Charpentier replicated this mechanism found in microbes to develop a ...

In 2012, scientists Jennifer Doudna and Emmanuelle Charpentier replicated this mechanism found in microbes to develop a ...

The original approach involved perturbing the cell nucleus with RNase A (an endoribonuclease that targets single-stranded RNA ... Secondary structure of SNORA74A was computed by R2DT. RNA end reads ...

It offers a fully automated, differentiable approach to RNA structure prediction without requiring expert knowledge or computationally intensive processes. RhoFold+ outperforms existing methods in ...

Single-stranded RNA is dynamic and highly structured ... Repetitive sequences, hairpin structures, modifications, and vulnerability to degradation—RNA harbors a number of challenges that ...

DNA double helix means that the two-stranded structure of DNA structure is common knowledge, RNA’s single-stranded format is not as well known. RNA can form into double-stranded structures, such as ...

Chromatin condenses further through a supercoiling process and packages into structures called ... but it is normally single-stranded. Another difference is that RNA does not contain the base ...

RNA is found in nature as a single strand folded onto itself, rather than a paired double strand. To understand what an individual RNA molecule does, its 3D structure needs to be deciphered at the ...

structures that are vital to their function. The biochemistry of an RNA molecule consists of a single strand made of a backbone with alternating ribose and phosphate groups. Ribose is a type of ...