Protein Kinase A (PKA) is regulated spatially and temporally via scaffolding of its catalytic (Cα) and regulatory (RI/RII) subunits by the A-kinase-anchoring proteins (AKAP). By binding to an AKAP11 ...

Pyroluria, also known as Pyrrole Disorder or Hemepyrrole (hemo=blood), is an inherited genetic defect in which the body ...

Titration curves are powerful tools for understanding the properties of acids and bases. One of the most important characteristics of an acid or base is its pKa value, which represents the acidity or ...

In the world of chemistry, equilibrium constants (Keq) and acid dissociation constants (pKa) play a vital role in understanding chemical reactions and their balance. The relationship between these two ...

Pyrrole disorder develops when there are too many pyrrole molecules in your body. These can strip your system of essential nutrients that play an important role in mood regulation. Doctors don’t ...

We also investigate the EDOT-Pyrrole and EDOT-Aniline copolymerization by enzymomimetic synthesis using two catalysts (Ferrocene and Hematin). It was found that, chemically, there are no detectable ...

Our earlier work revealed Cypher/ZASP as a PKA-anchoring protein (AKAP) that tethers PKA to phosphorylate target substrates. However, the downstream PKA effectors regulated by AKAP Cypher/ZASP and ...