Messenger RNA (mRNA) vaccines have been crucial to containing and controlling the ongoing Covid-19 pandemic. Advances in self-amplifying RNA technology promise to make them even more cost ...

The mRNA molecule consists of a 5′ UTR, protein-encoding open reading frame (ORF), 5′ cap, poly(A) tail, and 3′ UTR. UTR sequences from human β-globin are utilized for synthesizing mRNA.

Thermo Fisher Scientific Inc. (NYSE:TMO) is one of the most active stocks to buy according to analysts. On June 13, Ethris announced a collaboration with Thermo Fisher Scientific. The partnership aims ...

UTR Therapeutics Inc Announces IND submission to the US FDA for a First-in-Human Clinical Trial of an mRNA destabilizing drug targeting c-MYC driven cancers UTR Therapeutics Inc. Thu, May 8, 2025 ...

That left a question mark hanging over mRNA's other UTR. "A lot of attention has been paid to a few individual mutations in the 3'UTR, but not much attention has been paid to the 3'UTR itself.

Future Implications for mRNA Therapeutics . The fusion of cell-free gene synthesis and AI-driven optimization is redefining what’s possible in mRNA therapeutic development. ... A 5' UTR language model ...

For example, they have characterized the transcriptome (mRNA, lncRNA, and miRNA) of aortas in an atherosclerosis mouse model, both during disease progression and after regression following treatment.

This research indicates that Doxorubicin (Dox)-resistant TNBC cells exhibit increased glycolysis and ATP generation compared ...

Get Instant Summarized Text (Gist) Variations in mRNA length occur during atherosclerosis progression, with mRNAs showing shorter 5'UTR, 3'UTR, and coding regions.

Further analysis of the genes transcribed from the genomic island revealed that the 3'UTR of mRNA was processed to generate ManS, a novel small noncoding RNA of 80 nt in length.

Hsieh’s team has already showed that prostate cancer-associated mutations in the 5’UTR likely play an important role in prostate cancer. That left a question mark hanging over mRNA’s other UTR. “A lot ...

UTR Therapeutics Inc Announces IND submission to the US FDA for a First-in-Human Clinical Trial of an mRNA destabilizing drug targeting c-MYC driven cancers Provided by GlobeNewswire May 8, 2025 ...