the team believes Z-mRNA could be further improved through systematic engineering efforts. "The biggest implication of this work is that people don't have to be limited by those modifications that ...

mRNA therapeutics came about when biochemist Katalin Karikó and immunologist Drew Weissman discovered that inserting subtle chemical modifications into the bases – the building blocks – of ...

Duke researchers published a breakthrough in understanding m6A through the development of a genetically encoded sensor for the most abundant internal mRNA modification. These mRNA modifications ...

Creative Diagnostics, a leading manufacturer and supplier of antibodies, antigens and assay kits, has announced its ...

Zhang's team examined the molecular machine responsible for making this type of modification to the mRNA. They found that the protein Serrate interacts with this molecular machine to keep a ...

A tiny chemical modification commonly found on messenger RNAs plays a surprisingly large role in how cells respond to stress, according to a study led by Weill Cornell Medicine investigators.

N 6-methyladenosine (m 6 A) is the most extensive studied RNA modification across various species, and the important effect of m 6 A modification in immune system has been revealed in distinct ...

This tail is the limiting step for mRNA degradation. “We wondered, why can’t we make multiple tails?” Wang said. “That way, if we lose one, there can be many others.” Wang and her team first ...

N1-methylpseudouridine is a modification naturally found in some RNA molecules that’s attached to mRNA in vaccines to allow it to deliver its message to the cell without being destroyed by an ...

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