A new review was published in Volume 16 of Oncotarget on June 25, 2025, titled "Challenges and resistance mechanisms to EGFR ...

Many lung cancers are driven by mutations in the epidermal growth-factor receptor (EGFR), and so it makes sense that many successful modern treatments block EGFR activity. Unfortunately, cancers ...

EGFR pathway status was determined by previously published gene sets representing the whole pathway (defined by genes induced after removal of EGFR inhibition in a basal-like cell line model) 8; ...

3589 Background: KRAS mutated CRC patients are nonresponsive to anti-EGFR. In contrast, the clinical benefit of KRAS wild type is uncertain and needs further studies. Our retrospective study compared ...

In this study, we aimed at testing the hypothesis that ACh increases the proliferation rate of tenocytes through mAChR stimulation, as well as investigating whether this mechanism is mediated by the ...