During a Case-Based Roundtable® event, Joshua K. Sabari, MD, continued discussion of key outcomes from the MARIPOSA trial and toxicity management in patients with EGFR-mutated non–small cell lung ...

It is likely that in the near future, more comprehensive PGx studies that involved epigenetic factors, such as miRNA, DNA methylation and histone modification, will be the new norm for PGx ...

It shows how adjusting eGFR results for body surface may improve decision results. The National Kidney Foundation published a consensus document that advocates transition to race-free eGFR ...

1 Rybrevant is a bispecific antibody that targets EGFR and MET with immune cell-directing activity, whereas Lazcluze is a kinase inhibitor. The therapy is indicated for the treatment of adult patients ...

It was also confirmed that HDCA inhibited the Epiregulin (EREG)/Epidermal Growth Factor Receptor (EGFR) pathway by activating FXR, and a negative correlation between FXR and EREG was analyzed in CRC ...

Researchers at the University of Iowa (UI) Health Care and colleagues at the Texas Biomedical Research Institute, and Boston University, used human skin explants to track the cellular route that ...

Approvals are often required for the translocation of threatened or non-threatened species. It is always your responsibility to know the required approvals. Approvals vary between jurisdictions and ...

Assisted gene flow interventions such as plant translocations are valuable complementary techniques to habitat restoration. Bringing new genetic variants can contribute to increasing genetic diversity ...

Given the complexity of this genetic information (e.g., tumor mutation and gene overexpression, chromosomal translocation and germline variations), as well as the variable level of scientific ...