The EGFR pathway has an important role in modulating angiogenesis, metastasis, cell survival and proliferation (Figure 1); therefore, inhibition of this pathway is being explored for therapeutic ...
pathway. Overexpression of EGFR receptor may be detected in up to 90% of pancreatic tumors and ErbB- 2 expression in up to 21% of pancreatic tumors. Blockade of the activity of these receptors ...
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