Datroway received accelerated FDA approval for adults with EGFR+ advanced non-small cell lung cancer after EGFR-targeted and ...

The COCOON dermatologic management regimen significantly reduced the quality-of-life impact associated with Rybrevant (amivantamab-vmjw) plus Lazcluze (lazertinib) treatment versus the ...

Zhang N, Zeng Y, Du W, et al: The EGFR pathway is involved in the regulation of PD-L1 expression via the IL-6/JAK/STAT3 signaling pathway in EGFR-mutated non-small cell lung cancer. Int J Oncol ...

Table 1. Chromosome location, predicted target genes and functional consequences of miR-21, miR-155, miR-210, miR-221, miR-222 and miR-1233 in the context of renal cell carcinoma and EGFR pathway.

Activating mutations of EGFR identify a specific subtype of lung cancer, whose growth is dependent on EGFR pathway activation, which represents the leading pathway in inducing cellular ...

The HER3-directed ADC will be tested in patients whose disease had progressed despite earlier treatment with EGFR inhibitors, including third-generation drugs like AZ's Tagrisso (osimertinib).

Researchers assessed RAS status in patients' plasma samples using Sysmex's PCR-based OncoBeam RAS CRC Kit at various time points after progression on initial anti-EGFR treatment and identified 50 ...

Moreover, overexpression of nonoxidative pathway genes (TAL1 and TKL1) of the pentose phosphate pathway promotes the NADPH supply, resulting in a 16% increase in citronellol yield. Screening of ...