New link with the EGFR signaling pathway. Mutations leading to colon cancer affect a wide range of signaling pathways; these consist of chains of molecules that send messages to each other in ...

The researchers believe the EGFR pain pathway they found in mice and fruit flies is relevant to humans because of genetic results also reported in the paper on human cohorts with chronic facial ...

New link with the EGFR signaling pathway. Mutations leading to colon cancer affect a wide range of signaling pathways, these consist of chains of molecules, which send messages to each other in ...

Using tracer compounds, scientists have been able to track the cellular production of NADPH, a key coenzyme for making fat, through a pathway that has never been measured directly before. This ...

In this study, we demonstrated, for the first time, that activation of the epidermal growth factor receptor (EGFR)-mediated signaling pathway is involved in lenvatinib resistance in thyroid cancer ...

Laurent-Puig et al 2 retrospectively studied 173 advanced CRC cases collected from six hospitals, of which all but one received a cetuximab-containing regimen as second-line or greater therapy. They ...

Background: EGFR-driven NSCLCs are dependent on the EGFR pathway for proliferation which EGFR TKIs potently block. Progression occurs when resistance to erlotinib develops—through the emergence of ...

Patil’s research is looking at how that resistance occurs and how two other pathways, known as the EGFR and MET signaling pathways, play a role.

The researchers believe the EGFR pain pathway they found in mice and fruit flies is relevant to humans because of genetic results also reported in the paper on human cohorts with chronic facial ...