The researchers conclude, "Our data provide evidence that BUB1 protein and its kinase activity may regulate EGFR activation, endocytosis, degradation, and downstream signaling without affecting ...

CS2011 is a bispecific antibody with high binding affinity to both EGFR and HER3. It effectively blocks downstream signaling of both targets, thereby inhibiting tumor growth on EGFR/HER3 positive ...

Creative Biolabs recently updated its antibody chip platform, expanding product arrays for phosphorylation signaling and cytokine detection. SHIRLEY, NY, UNITED STATES, May 27, 2025 /EINPresswire.com/ ...

The link between EGFR signaling and FBXW7 mutations is important to investigate in order to improve treatment options for colorectal cancer. Currently, many patients are treated with EGFR ...

Cancer cells may acquire the capacity for autonomous and dysregulated proliferation through the uncontrolled production of specific molecules that promote cell growth (growth factors) or through ...