News

EMBO Press3h
NRF2 modulates WNT signaling pathway to enhance photodynamic therapy resistance in oral leukoplakia
Photodynamic therapy (PDT) resistance limits treatment efficacy in oral leukoplakia (OLK). This study identifies p-NRF2 as a ...
emjreviews.com1d
Overcoming Resistance: How Targeted Approaches Are Changing Management of Advanced EGFR-Mutant Lung Cancer and Paving the Way for Precision Medicine
EGFR-TKIs are molecules that bind to the adenosine triphosphate (ATP) binding domain of the EGFR protein, thereby interrupting the downstream signalling pathway. 1 They have significantly improved ...
AHA/ASA Journals4d
High Dietary Phosphate Intake Induces Hypertension and Sympathetic Overactivation Through Central Fibroblast Growth Factor Receptor Signaling
BACKGROUND: Recent studies have highlighted the deleterious role of high phosphate intake in hypertension by means of ...
ahajournals.org5d
Autocrine Signaling in Cardiac Remodeling: A Rich Source of Therapeutic Targets
Communication between these different cell types, also called paracrine signaling, is essential for normal cardiac function, but also important in cardiac remodeling and heart failure. Systematic ...
Newseria BIZNES14d
New Antibody Arrays by Creative Biolabs Boost Immune Signaling Research
Creative Biolabs recently updated its antibody chip platform, expanding product arrays for phosphorylation signaling and ...
Frontiers15d
Mechanism of action and potential therapeutic targets of TGF-β-related signaling pathway and its downstream miRNA expression in pulmonary arterial hypertension
In recent years, the TGF-β signaling pathway and miRNAs have played important roles in the pathogenesis of PH. TGF-β regulates the proliferation, migration and fibrosis of vascular smooth muscle cells ...