“Our data provide evidence that BUB1 protein and its kinase activity may regulate EGFR activation, endocytosis, degradation, and downstream signaling without affecting other members of the ...

As explained by Patel, systemic EGFR-targeted therapies block EGFR activity and downstream signaling in multiple organs -- including the skin -- which can lead to subsequent dysregulation of skin ...

In a recent study, researchers have uncovered the biological trigger behind the dangerous immune-related adverse events ...

CS2011 is a bispecific antibody with high binding affinity to both EGFR and HER3. It effectively blocks downstream signaling of both targets, thereby inhibiting tumor growth on EGFR/HER3 positive ...

Creative Biolabs recently updated its antibody chip platform, expanding product arrays for phosphorylation signaling and cytokine detection. SHIRLEY, NY, UNITED STATES, May 27, 2025 /EINPresswire.com/ ...