A new method uses magnetic beads to hold molecules in place, keeping the sample intact and reducing sample loss by a ...

and the magnetic beads to the grid. With the particles securely in place, blotting could then be done safely, with far less sample loss. "In traditional cryo-EM, the target molecules just float ...

This process tethered the target molecules to the magnetic beads, and the magnetic beads to the grid. With the particles securely in place, blotting could then be done safely, with far less sample ...

This useful manuscript describes cryo-EM structures of archaeal proteasomes that reveal insights into how occupancy of binding pockets on the 20S protease regulates proteasome gating. The evidence ...

They say a picture is worth a thousand words. But it takes millions of pictures to understand the intricate chemistry of an ...

Researchers explore how merging X-ray imaging and cryo-EM could enable real-time, high-resolution views of biology, advancing molecular films and drug design. By combining ideas and approaches ...

These fundamental findings offer a novel mechanism by which rubrerythrin tubules encapsulate encapsulin to prevent oxidative stress in Pyrococcus furiosus. However, there are a few reasonable concerns ...

Cryo-electron microscopy (cryo-EM) has revolutionalized our understanding of the intricate molecular machinery that governs life. It has elucidated the three-dimensional (3D) structure of biological ...