demonstrate that RIOK1 phase separation leads to PTEN mRNA sequestration and pentose pathway activation ... in CTNNB1 (encoding for b-catenin) leading to deregulated Wnt/β-catenin signaling ...

(5) The authors present evidence of phylogenetic conservation of the pathway ... via activating Wnt signaling. By performing a series of biochemical experiments, they also showed that bcas2 ...

While current studies have unequivocally shown that NUSAP1 positively modulates the Wnt/B-catenin pathway through multiple mechanisms, including B-catenin nuclear translocation, SUMOylation of TCF4, ...

Photodynamic therapy (PDT) resistance limits treatment efficacy in oral leukoplakia (OLK). This study identifies p-NRF2 as a ...

Neuro-immunological interactions have emerged as pivotal regulators of chronic-wound repair, integrating signals from the ...

Dickkopf-1 (DKK1) and sclerostin (SOST) are both upstream inhibitors of the Wnt/β-catenin pathway. Given that AS is associated with new bone formation we are interested in the molecular pathways that ...

Methods Quantitative PCR, western blotting, immunohistochemistry and immunofluorescence were used to study the expression pattern of Wnt2 and its effect on the Wnt/β-catenin pathway. A Wnt2-secreting ...

More UOG first-year students and sophomores also plan to take this career pathway, the university added. Under a program called “2+2," students who completed the first two years of their ...

Move over, Penrith – the NRL has a new pathway to rugby league stardom. An analysis of the Roosters squad dispels the myths about the club’s so-called lack of juniors, but also has the ...

This important work supports the role of breast carcinoma amplified sequence 2 (Bcas2) in positively regulating primitive wave hematopoiesis through amplification of beta-catenin-dependent (canonical) ...