Each protein or peptide consists of a linear sequence of amino acids. The protein primary structure conventionally begins at the amino-terminal (N) end and continues until the carboxyl-terminal (C ...

THE weakest point in the DNP-method 1 is the destruction of the N-terminal DNP-amino-acid which occurs under ... is the time at which DNP-peptides are no longer present; this is different with ...

They then further engineered the microbe to substitute the terminal alkyne amino acid for all the methionines in the microbe’s proteome. Chang plans to explore additional bioorthogonal chemistry ...