GIST is an acronym that stands for gastrointestinal stromal tumor. This type of cancer starts in interstitial cells of Cajal (ICCs), which are special cells that line the walls of the ...

Most advanced gastrointestinal stromal tumors (GISTs) start with cancer-causing cell changes, or mutations, in specific genes. Changes in proteins called KIT and PDGFRA most commonly cause this ...

A gastrointestinal stromal tumor (GIST) is a cancerous tumor that grows in the digestive tract. Surgery can help remove the entire tumor. There are several procedures, including laparoscopy or ...

If you have advanced gastrointestinal stromal tumor (GIST), you may not know anyone else with the disease. This may leave you with a lot of questions about what life will be like with this rare ...

GISTs are a rare type of cancer that develops in the digestive tract’s connective tissue, specifically from cells that help regulate muscle contractions. GISTs are primarily driven by genetic ...

Gastrointestinal stromal tumors (GIST) are rare mesenchymal tumors and were among the first solid tumor types for which such a novel treatment (in this case imatinib) became available. The ...

The C2 subtype, defined as CD8 + inflamed, comprises high-risk intestinal GISTs with high infiltration of immune cells, especially CD8 + T cells, suggesting that these tumors may benefit from a ...

Preclinical data has showing compelling findings for HT-KIT among patients with rare and aggressive KIT-driven cancers, ...

Huntsman Cancer Institute’s Sarcoma Service has a specialist team that treats soft-tissue sarcomas that form in the abdomen. Here are some soft-tissue sarcomas of the abdomen: Gastrointestinal stromal ...

According to the 2022 national cancer registration statistics, the number of gastric cancer patients was 356,507, accounting ...

Thus, several potential systemic treatment options currently exist for patients whose tumors progress during ... of treatment options for patients with GIST will expand. Before such novel ...

A recent study offering a comprehensive view of the genome and transcriptome of gastrointestinal stromal tumors (GISTs) has introduced a new, multi-omics-based molecular classification of these ...