Using artificial intelligence, researchers show how γ-secretase recognizes substrates - an important advance for fundamental and translational research. The γ-secretase enzyme is capable of cleaving ...

Scientists identified the mechanism by which a sea cucumber molecule inhibits sulfatase-2, an enzyme that’s often upregulated ...

The mechanisms by which proteins sense voltage is diverse: ion channels have a conserved, positively charged transmembrane region that moves in response to changes in membrane potential, some G ...

A group of researchers at the VIB‑UGent Center for Medical Biotechnology has developed a new platform to isolate and analyze ...

AbCellera Biologics Inc. (NASDAQ: ABCL) is one of the 13 Stocks Under $5 With High Upside Potential. On May 16, Truist ...

InnoCare receives China NMPA approval to conduct clinical trial of a novel B7-H3 targeted ADC ICP-B794: Beijing Monday, July 7, 2025, 15:00 Hrs [IST] InnoCare Pharma, a leading bi ...

Center for Drug Evaluation (CDE) has granted approval to the investigational new drug (IND) application of InnoCare Pharma to ...

InnoCare Pharma (HKEX: 09969; SSE: 688428), a leading biopharmaceutical company focusing on the treatment of cancer and autoimmune diseases, announced today the approval of the Investigational New ...

Vertex Pharmaceuticals (Nasdaq: VRTX) today announced that the European Commission has granted approval for ALYFTREK ® (deutivacaftor/tezacaftor/vanzacaftor) for the treatment of people with cystic ...

The 99 amino acid C-terminal fragment of amyloid precursor protein (C99), consisting of a single transmembrane (TM) helix, is known to form homodimers. Homodimers can be processed by γ-secretase to ...

They analyzed the protein–nanoparticle interactions using thioflavin T (ThT) fluorescence, Fourier transform infrared spectroscopy (FT-IR), and circular dichroism (CD).

Secreted and membrane proteins may be of particular importance in mammalian development, as suggested by a large expansion of new extracellular protein architectures in humans compared with worms ...