Human IgG1 Fc with effector function knock-out (LALA) mutations was used as Fc-region for all TcEs, which additionally contained Genentech’s knob-in-hole mutations in the CH3 domain to promote ...

In 2025, the shift knob remains a tactile link between driver and machine for those who favor engagement over automation. Whether it’s the engagement of a traditional manual shift knob or the ...

Memory resides within a dense network of billions of neurons within the brain. We rely on synaptic plasticity—the strengthening and modulation of connections between these neurons—to ...

Synaptic transmission is the biological process by which a neuron communicates with a target cell across a synapse. Chemical synaptic transmission involves the release of a neurotransmitter from ...

LICONN is the first technology beyond electron microscopy capable of reconstructing brain tissue with all the synaptic connections between neurons. It also opens up the possibility of visualizing ...

The researchers claim LICONN is the first technology beyond electron microscopy (EM) that is capable of reconstructing brain tissue with all the synaptic connections between neurons. It also opens ...

Knob Creek is adding a cask strength bourbon and rye to its popular private barrel selection program. The barrels will be bottled without any dilution at a range from approximately 110–130 proof ...

Aptly situated within the exceptionally maintained resort style complex of "Half Moon Bay Golf Resort", Natasha Whalley-Thompson is proud to welcome this one bedroom apartment to the property ...

The goal is to make it as far as possible while collecting cash and door knobs to make your next run easier. So, how long can you survive? Callum Williams is an IGN freelancer covering features ...

This work has crated the map of synaptic connectivity between the inputs and outputs of song premotor nucleus, HVC in zebra finches to understand how sensory (auditory) to motor circuit interact to ...

The V1 Max provides the best typing experience and the most extra features—RGB, hot-swap, wireless, a knob, and easy programmability—for a surprisingly reasonable price. The V2 Max is ...