This is a useful study in the role of CHI3L1 in Kupffer cells, the macrophages of the liver, showing that CHI3L1 alters glucose regulation in obesity. Specifically, Chi3l1 protects glucose-dependent ...

It follows a previous report showing that the Werner syndrome protein WRN and its interacting protein WRNIP1 are indispensable for translesion DNA synthesis (TLS) by Y-family DNA polymerases (Pols).

Background Chronic inflammation and elevated reactive oxygen species are key contributors to hepatocellular carcinoma (HCC) ...

While chemiluminescence has been the traditional approach to western blot detection, this strategy is being progressively supplemented or replaced with fluorescence-based detection. With the ...

We understand that gaining publication-quality results straight away is not the norm when performing western blot. This 32-page handy guide provides tips and tricks to obtain high-quality, publishable ...

Hydrolysis was calculated using the extinction coefficient of 6,230 μM −1 cm −1 for NADH. b, Western blot of a His 6 -ClpX–ClpP pull-down using Ni +2 -NTA resin.

An interaction between two proteins points to a molecular basis for memory. But how do memories last when the molecules that ...

Oncogenic YAP accelerates S-phase entry by shortening G1, leading to replication stress and sensitivity to CHK1 inhibition.

The multiplex fluorescent detection and chemiluminescent imaging capabilities of the FluorChem Q provide a complete solution for quantitative Western blot imaging and analysis.