Vincristine monotherapy triggers NF-κB activation, inducing OIP5 expression linked to cancer cell resistance against vincristine. The engineered sgRNA, housing the NF-κB aptamer, competitively ...

The combination of vincristine and irinotecan is highly active in metastatic rhabdomyosarcoma. The different mechanism of action and nonoverlapping toxicity profile with VAC makes this combination an ...

Paclitaxel and vincristine potentiate adenoviral oncolysis that is associated with cell cycle and apoptosis modulation, whereas they differentially affect the viral life cycle in non-small-cell ...