Objectives: To assess the efficacy and tolerability of valsartan and valsartan plus hydrochlorothiazide (HCTZ), given alone or as part of a combination regimen with other antihypertensive agents ...

The 4,822-patient study missed statistical significance for a composite primary endpoint of reducing cardiovascular death and total heart failure hospitalisations by 13% compared with valsartan ...

Valsartan 80 mg/day was administered to patients who did not respond to diuretics during heart failure exacerbation in the conventional group (n = 21). Therefore, adding carvedilol to existing ...