BACKGROUND/AIMS Dendritic cells (DC) and macrophages are components of the immune cell populations in the uveal tract whose density, distribution, turnover, and function may play a role in the ...

Uveal melanoma is the most common primary malignancy of the eye and frequently leads to metastatic death. Until the mid-20th Century, the only treatment for uveal melanoma was enucleation. Since ...

Patients with uveal melanoma face many threats: early death, pain, visual handicap, and facial disfigurement, which result in loss of income and independence, with restrictions on occupational ...

Clinical-stage biotech iOnctura has received US Food and Drug Administration (FDA) clearance to carry out investigations into a treatment aimed at tackling rare cancers. The FDA has granted its ...

Classified as a type of anterior uveitis, iritis involves the inflammation of the front section of the uveal tract in the eye. Untreated, it can lead to serious complications affecting vision.” ...

The summer of 2023 saw the approval of a new treatment option for certain patients with uveal melanoma, a form of cancer that begins in the eye and remains a challenge to treat. Richard Staines ...

The association of vitiligo with inflammation of the uveal tract is well established. The relationship between vitiligo and hypopigmentation and/or degeneration of the retinal pigment epithelium (RPE) ...

1 UCD Conway Institute, University College Dublin, Dublin, Ireland 2 UCD School of Biomolecular and Biomedical Science, University College Dublin, Dublin, Ireland Uveal melanoma (UM) is the most ...

Aqueous humor is produced via active secretion by the ciliary body, which is part of the uveal tract between the iris and the choroid. The ciliary body consists of ciliary processes and the ...