With several hundred kinases encoded in the human genome, almost every signal transduction process is influenced by interconnected phosphorylation events. Deregulation of kinase activity has been ...

The simulated models revealed that an intricate interplay of events is taking place between the EC and TM regions ultimately affecting the intracellular immunoreceptor tyrosine-based ... signaling ...

1 pM), consistent with its proposed mechanism of action as an inhibitor of signal transduction, and growth-inhibited cells were arrested in G 1 (Gibbons et al., 2000). In studies involving ...

In a study published in Science Advances, University of Alabama at Birmingham researchers led by Kasey Brida and Jeremy Day, ...

A study conducted by researchers at the Center for Cell-Based Therapy (CTC) highlights key proteins and signaling pathways ...

Lung cancer is the malignant tumor with the highest incidence and mortality rate in the world. With the in-depth research of ...