The insulin receptor (IR) is a prototypical receptor tyrosine kinase that orchestrates critical cellular processes, including metabolism, cell growth and differentiation. Activation of the IR ...

Kym-1 rhabdomyosarcoma growth depends on functional insulin/IGF signal pathways In ... GST-[K71A] Erk1 agarose conjugate and non-active GST-MAP kinase kinase 1 (GST-MEK1) were from Upstate.

Biodexa Pharmaceuticals PLC Result of General Meeting Biodexa Pharmaceuticals PLC (“Biodexa” or the “Company”) (NASDAQ: BDRX), a clinical stage biopharmaceutical company developing a pipeline of ...

Alumis Inc. (Nasdaq: ALMS), a late-stage biopharma company developing next-generation targeted therapies for patients with immune-mediated diseases, today announced that Martin Babler, President and ...

Biodexa Announces Recruitment of First Patient in Phase 2 Study of Tolimidone in Type 1 Diabetes ...

Issued shares, total voting rights, market capitalization As of May 29, 2025, there were 50,506,308,922 ordinary shares, equivalent to 5,050,630 American Depositary Shares (ADSs), outstanding. The ...

Biodexa Pharmaceuticals PLC Shareholder Update Biodexa Pharmaceuticals PLC ("Biodexa" or the "Company") (Nasdaq: BDRX), a clinical stage biopharmaceutical company developing a pipeline of ...

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Identifying proteomic signatures of insulin resistance in fasting muscle offers insights for personalized type 2 diabetes ...

There are conflicting data regarding the effects of TK inhibitors on tumor immunity (Table 2). Some reports demonstrated the immunostimulatory effects of a TK inhibitor, but others reported the ...

No writing assistance was utilized in the production of this manuscript. Tyrosine kinase inhibitors (TKIs) are used for the targeted treatment of cancer. TKIs produce a range of serious adverse ...