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Dr. Elise Olsen and associates (Olsen et al., 1997) discovered that reducing the frequency of tretinoin 0.05% cream from once daily to 3 times per week maintains, and in some cases, possibly ...

Mild comedonal (noninflammatory) acne may be treated with once daily application of a topical retinoid such as adapalene (0.1% cream; 0.1% gel; 0.1% solution; 0.1% pledgets), tretinoin (0.025% ...