Kanazawa University, report in Small, on how short peptides self-assemble linearly on atomically-thick solid surfaces, such ...

DelveInsight’s, “Chronic Lymphocytic Leukemia Pipeline Insight 2025” report provides comprehensive insights about 55+ companies and 60+ pipeline drugs in Chronic Lymphocytic Leukemia (CLL) pipeline ...

CD94 (orange) and NKG2A (yellow) are transmembrane proteins, the latter containing an intracellular domain with two ITIM regions. Target cells (e.g., cancer, senescent cells, and healthy cells) ...

Human signal peptide peptidase may represent another family of aspartic proteases that promote ... Weihofen et al. identified human SPP as a polytopic membrane protein with sequence motifs ...

Most computational methods for transmembrane protein topology prediction rely on compositional bias of amino acids to locate those hydrophobic domains in transmembrane proteins. Because signal ...

In human cells, approximately 30% of all polypeptides enter the secretory pathway at the level of the endoplasmic reticulum (ER). This process involves cleavable amino-terminal signal peptides (SPs) ...

G-protein coupled receptors (GPCRs) play pivotal roles in signaling pathways and are the most common membrane proteins. Implicated in many diseases, they are an attractive therapeutic target.

HCV belongs to the genus Hepacivirus (family Flaviviridae) and harbors a positive-sense, single-stranded RNA genome; its viral RNA is translated into a single polyprotein of ∼3,000 amino acids that is ...

The link between signal peptides and transmembrane domains is further reinforced by the fact that the translocation activity of the Sec machinery is required for correct insertion of membrane proteins ...

Members of the Gx GD ‐type intramembrane aspartyl proteases have emerged as key players not only in fundamental cellular processes such as B‐cell development or protein glycosylation, but also in ...