Fat necrosis in the breast happens when fat tissue in your breast dies, usually because of an injury or procedure. It's not dangerous to your health, and you may not feel any discomfort.

More information: Jacob W Klemm et al, Regeneration following tissue necrosis is mediated by non-apoptotic caspase activity, eLife (2025). DOI: 10.7554/eLife.101114.3. Provided by eLife.

A 69-year-old woman presented with a large, deep area of skin necrosis on the right breast. One month earlier, the patient had undergone a surgical treatment for a frontal-parietal meningioma.

Skin necrosis due to local arterial thrombosis is rare, but may be seen in other parts of the body, such as the trunk and the upper extremities.

But "unprogrammed" cell death, or necrosis, is an uncontrolled and catastrophic process that leads to tissue degeneration and biological decline. At the center of the necrotic process is calcium, a ...

Warfarin-induced skin necrosis (WISN) occurs in only 0.01%-0.1% [1,4,5] of patients taking the drug; the incidence is higher in middle-aged women. This side effect typically appears during the ...