Thiazides, thiazide-like and loop diuretics are commonly prescribed to manage hypertension and heart failure. The main mechanism of action of these diuretics involve inhibition of Na + reabsorption in ...

However, evidence from this and other clinical trials have also found an increased incidence of new onset diabetes among those patients receiving thiazide diuretics. The mechanisms responsible for the ...

4 Because there are ample downstream sites for sodium uptake, CAIs have weak diuretic action, and are primarily ... you got them there slowly.” DCT diuretics (thiazides) Similar in chemical structure ...

The ability of thiazide-type diuretics to reduce BP seems to be linked to the presence of functioning renal tissue; thus, these drugs will not reduce BP in hemodialysis patients. [6] ...

Diuretics, also known as “water pills,” increase the flow of urine and help your kidneys remove salt from your body. Diuretics can help various medical conditions caused by too much fluid. They lower ...

Thiazide diuretics have been commonly used as first-line agents ... Usually, your healthcare provider will prescribe either chlorthalidone or HCTZ. These drugs have the same action mechanism, so ...

These patients were compared with those taking thiazide diuretics, due to its non-vasodilatory antihypertensive mechanism. Results showed that 12,135 patients developed acne within 5 years of ...

After these initial findings, the authors started to analyze groups of candidate genes involved in related mechanisms of action. However, all of these papers considered the genes one by one.

The VUMC team next plans to assess the mechanisms by which thiazide diuretics prevent kidney stone formation. Triozzi concluded in the news release, “Our study highlights the importance of considering ...

Thiazide diuretics are recommended by international guidelines for the prevention of calcium kidney stones with long-term safety data." The all-VUMC team of researchers plans to investigate the ...

Future Research and Implications The Vanderbilt research team plans to delve deeper into the mechanisms by which thiazide diuretics lower kidney stone risk. Their findings underscore the ...