Comprehensive knowledge of cancer biology and the tumor microenvironment, including cell–cell communication, cellular characteristics, cell–matrix interactions and abnormal physiology, is crucial to ...

This infographic highlights single-cell sequencing workflows, multiomics integration and emerging applications that are ...

But in cancer cells, these elements can become demethylated, enabling them to be expressed (1). Some transposable elements code for proteins such as endonuclease and reverse transcriptase (2). The ...

Nature Cell Biology - This month, we launch a series of specially commissioned review and perspective articles on cancer cell biology, covering key topics and recent advances in understanding the ...

Recent research on MCL-1, a critical protein that is an attractive target for cancer drug development, helps explain why some ...

In a bid to better understand how cancer cells power their explosive growth and spread, scientists at Johns Hopkins Medicine ...

Mutations in the cancer cells themselves or changes to the niche may later awake these dormant cells, enabling them to proliferate and form metastatic tumors. Dissemination: In some cancers, including ...

In a 2016 proof-of-concept study, the team showed that treating a dish of breast cancer cells with the experimental drug exposed them to killing by natural killer cells.

Cancer cells are driven by the same imperative guiding all living things: to grow, survive and reproduce. Although cancer's evolutionary underpinnings have been recognized since the 1950s ...

Triple-negative breast cancer (TNBC) is the most aggressive form of breast cancer, and TNBC patients with obesity-driven diabetes often have worse outcomes. More than 120 million Americans suffer ...

Immunotherapy, which uses programmed immune cells to selectively destroy cancer cells, has transformed cancer treatment. However, cancer cells have developed immune evasion strategies, leading to ...