Background: Mycophenolate mofetil (MMF) inhibits IMPDH and disrupts de novo purine synthesis which is preferred by glioblastoma (GBM) whilst normal brain prefers resource efficient salvage pathway. A ...

SAN CLEMENTE, Calif.-- (BUSINESS WIRE)-- #CLIFighters --Reflow Medical, Inc., a leading developer of innovative medical devices focused on complex cardiovascular disease, announced that the U.S. Food ...

May 29, 2025—Reflow Medical, Inc. announced that the FDA has granted de novo clearance for the company’s Spur peripheral retrievable stent system for the treatment of de novo or restenotic lesions ...

Tour de France 2025 introduces an entirely new refuelling mechanism, revolutionizing race strategies. From now on, at the start of your races, you'll only have access to one type of feed.

News Release 24-Mar-2025 Researchers achieve de novo biosynthesis of plant lignans using synthetic yeast consortia Peer-Reviewed Publication Dalian Institute of Chemical Physics, Chinese Academy ...

The FDA issued its first stamp of approval for a cell or gene therapy back in 2017 to Novartis' Kymriah. Now, seven years and many approvals later, innovation in the space has hit new heights with ...

Preclinical data show intracellular uptake of a ligand-siRNA conjugate in vitro using megalin, an endogenous, endocytic recycling receptor on proximal tubular cells of the kidney Megalin-mediated ...

New research now demonstrates an alternative approach, a synthesis-free method that uses a universal DNA template to encode data. (Nature 2024, DOI: 10.1038/s41586-024-08040-5) ...

Cancer biologists discover a new mechanism for an old drug Study reveals the drug, 5-fluorouracil, acts differently in different types of cancer -- a finding that could help researchers design ...

Remodeling of the secretory pathway is coordinated with de novo membrane formation in budding yeast gametogenesis. iScience, 2024; 27 (10): 110855 DOI: 10.1016/j.isci.2024.110855 ...

News Release 27-Sep-2024 Elucidating the mechanism underlying de novo membrane formation during gametogenesis Peer-Reviewed Publication University of Tsukuba ...