Programmed cell death serves as a critical defense mechanism during viral infection. The kinases RIPK1 and RIPK3, central ...

How do breast cancer cells bypass the blood-brain barrier (BBB) to colonize the brain? This study uncovers a ...

The FDA approved taletrectinib for ROS1-positive NSCLC. The agent shows efficacy for both new and pretreated cases, including ...

More than 40 million people worldwide are living with HIV-1, which continues to be a major global health challenge due to its ...

Figure 1 Toll-like receptors (TLRs) and their signaling pathways. TLRs are situated either on the cell surface (such as TLR1/2, TLR2/6, TLR4, TLR5) or intracellularly (like TLR3, TLR7/8, TLR9). With ...

Objective Based on Toll Like Receptor 4 (TLR4)/Nuclear Factor-κB (NF-κB) Exploring the effects of Licochalcone A (LCA) on the proliferation, invasion, and drug resistance of glioma cells through ...

Notably, our results highlight the critical role of the PGE2 pathway and TLR4 signaling in the activation of lipolysis. Following the acute inflammatory phase, endotoxemia reduces lipolysis intensity ...