(Figure 1.) The impulse of an action potential causes the release of acetylcholine from synaptic vesicles (each containing about 10,000 molecules of acetylcholine) diffusing across the 20-nm gap ...
Université Paris-Saclay, Inserm, CNRS, CEA, Laboratoire d’Imagerie Biomédicale Multimodale (BioMaps), Service Hospitalier Frédéric Joliot, 4 place du général Leclerc, Orsay 91401, France Department of ...
State Key Laboratory of Advanced Drug Delivery and Release Systems, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, China ...
Get Instant Summarized Text (Gist) Extracellular vesicles (EVs) contain ion channels that maintain their structural integrity and function during cell-to-cell cargo transport. These channels ...
The paper was published Jan. 2 in Nature Communications. Extracellular vesicles carry proteins and other molecules from donor to recipient cells to alter physiological and biological responses.
Only molecules carried by EVs with ion channels were able to repair the heart damage. “We have not only discovered ion channels in these vesicles. We have recorded functional ion channels for ...
Acetylcholine plays a vital role as a neurotransmitter that oversees cognitive tasks, memory, and the regulation of mood. With aging, our body’s generation of acetylcholine decreases, which ...
Mutations in different synaptic molecules give rise to CMS. These molecules include choline acetyltransferase (CHAT), acetylcholinesterase (ACHE), the different acetylcholine receptor (ACHR ...
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