The impulse of an action potential causes the release of acetylcholine from synaptic vesicles (each containing about 10,000 molecules of acetylcholine) diffusing across the 20-nm gap to the ...

Synaptic vesicle exocytosis is the biological process by which a synaptic vesicle fuses with the plasma membrane of the pre-synaptic axon terminal and releases its contents into the synaptic cleft.

Synaptic vesicle endocytosis is the biological process by which the plasma membrane at the pre-synaptic axon terminal invaginates to create membrane-bound synaptic vesicles.

Young and his team first confirmed that the proteins play several key roles in ensuring that synaptic vesicles which contain ...

Prominent clusters include synaptic vesicle proteins, as well as proteins involved in energy metabolism and ion homeostasis. Using subcellular fractionation and electron microscopy we provide further ...

These results suggest that Aβ and αS cooperate to accelerate the production of toxic oligomers, whose main toxicity is the inhibition of vesicle fusion and consequently the disruption of synaptic ...

Synaptic density in L1a and L1b of the human TLN Synaptic density measurements serve as a valuable tool for quantitatively characterizing the synaptic organization of a specific cortical layer, ...