Homeostatic plasticity, the brain's method of preserving equilibrium in neural circuits, relies heavily on spontaneous ...

This study leverages cryo-correlative light and electron microscopy (cryo-CLEM) with triple fiducial markers to achieve ...

How do we think, feel, remember, or move? These processes involve synaptic transmission, in which chemical signals are ...

A collaborative study led by Professor Vittoria Raffa at the University of Pisa and Assistant Professor Fabian Raudzus ...

How do we think, feel, remember, or move? These processes involve synaptic transmission, in which chemical signals are transmitted between nerve cells using molecular containers called vesicles. Now, ...

How do we think, feel, remember, or move? These processes involve synaptic transmission, in which chemical signals are transmitted between nerve cells using molecular containers called vesicles.

The laboratory of Ege Kavalali, professor and chair of the Department of Pharmacology, published a paper in Nature ...

Researchers have used cryo-electron tomography to uncover new details of the molecular structure of synaptic vesicles, which help transport neurotransmitters in the brain. The study could inform ...

Imaging synaptic vesicles in 3D Max Delbrück Center researchers have used cryo-electron tomography to uncover new details of the molecular structure of synaptic vesicles, which help transport ...

Researchers have used cryo-electron tomography to uncover new details of the molecular structure of synaptic vesicles, which help transport neurotransmitters in the brain.

Once the VMAT has packed the vesicle with monoamines, the vesicle can then move toward the synaptic gap, into where it releases the chemical compounds. VMATs belong to the SLC18 family of ...