Utilizing a high-throughput screening campaign and subsequent structure-guided design, we identify small-molecule inhibitors of this interaction with potent in vitro binding affinity and report ...

An active structure fire has been reported on Hildebrant Drive in Maineville. The fire has been reported on the 100 block of Hildebrant Drive near State Route 48. No injuries or residents trapped ...

Fire crews responded to a structure fire at 90 Salem Road in Billerica, Massachusetts, on Monday evening. According to social media reports, heavy smoke and flames were seen billowing from the ...

OpenAI, in which Microsoft has invested more than $13 billion, outlined plans in December to convert its for-profit arm into a public benefit corporation (PBC), a structure designed to balance ...

A lot of organizations like to say publicly that “the client comes first.” It’s the right thing to say. It’s the easy thing to say. But using that statement to guide the way your ...

Despite these differences, your organizational structure has to satisfy basic manufacturing requirements and fulfill common operational functions. Once you have set up your organization to meet ...

A research team led by Dr. Weizheng Fu and Professor Yuichi Otsuka from Nagoya University's Institute for Space-Earth Environmental Research (ISEE) has captured the detailed 3D structure of ...

Since small businesses can't change the structure of the market, you have to analyze how it affects your firm, identify the negative aspects and change your company's approach to the market to ...

Rely on an impressive short kicking game. Jarome Luai, the four-time premiership winner at Penrith, was recruited by the Tigers to provide the structure. Galvin was meant to bring the flair.

Structure-based drug design is the design and optimization of a chemical structure with the goal of identifying a compound suitable for clinical testing — a drug candidate. It is based on ...

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CIRIMAT UMR CNRS 5085 / LCMIE, Centre Interuniversitaire de Recherche et d'Ingénierie des Matériaux, Université Paul-Sabatier, 31062 Toulouse Cedex 4, France and NUMAT, Department of Subatomic and ...