The switch from fetal γ-globin to adult β-globin is controlled by BCL11A. Genetic manipulation of BCL11A improves disease outcomes by turning γ-globin expression back on to compensate for ...

Hydrogels have been used in a multitude of biomedical applications for this reason. The purpose of this review is to explore some of the hydrogel systems that have been designed for this purpose, ...

Prolonged apnea after succinylcholine may be due to a marked deficiency of pseudocholinesterase, the plasma enzyme that normally hydrolyzes and inactivates the drug. Low pseudocholinesterase ...

Introduction Since the 1950s, cardiac arrest has been observed in burn patients receiving succinylcholine. A decade later, hyperkalemia was determined to be the cause of the cardiac arrest in ...

(RTTNews) - CytoDyn Inc. (CYDY.OB), a biotechnology company, Tuesday announced new data suggesting a novel mechanism of action of leronlimab for the treatment of solid tumors.

Theralase(R) Has Discovered a New Mechanism of Action in Its War on Cancer; Specifically, Ruvidar's(TM) Ability to Inhibit DeUbiquitinating Enzymes, an Important Class of Enzymes Which Have Been ...

Circle Pharma, a clinical-stage biopharmaceutical company focused on developing cell-permeable macrocycle therapeutics, today announced a late-breaking poste ...

How Well Did the Mysterious Antikythera Mechanism Actually Work? Historians think the 2,000-year-old device was used to predict the positions of celestial bodies. A new digital simulation suggests ...

Objectives To evaluate the optimal dose of succinylcholine for laryngeal mask airway (LMA) insertion and all related morbidities. Design Systematic review, meta-analysis and metaregression of ...

This finding is consistent with 8-azaguanine’s known mechanism of action as an antimetabolite that resembles the purine base guanine (42) and reportedly the polyploid-specific disruptor of ...

With this approval, we'll have a unique mechanism of action. We'll have another treatment option [with] reduced resistance due to its mechanism of action, and I think that's really going to drive ...

The manuscript shows the mechanism of action of quinofumelin, a novel fungicide, against the fungus Fusarium graminearum. Through omics analysis, phenotypic analysis, and in silico approaches, the ...