A 35-year-old man presents with a chief complaint of purple discoloration of his toes and associated skin lesions that have ...

The U.S. Food and Drug Administration has approved GSK's autoinjector of Benlysta (belimumab) for subcutaneous injection in ...

Lupus, an autoimmune disorder, presents skin manifestations like the butterfly rash, often mimicked by conditions such as ...

Cohort A focused on patients with CLE or SLE with active lupus rash and evaluated organ-specific disease activity using the Cutaneous Lupus Erythematosus Disease Area and Severity Index Activity ...

Background Many investigators have explored pathways upregulated in SLE and CLE. Few reports studied key downregulated pathways and mediators. Using unbiased proteomic technique, we have previously ...

Systemic lupus erythematosus (SLE), an autoimmune disease with heterogeneous clinical manifestations, is associated with significant morbidity and mortality. 1–3 Any organ can be affected in SLE, but ...

An oral therapy targeting toll-like receptors (TLR) 7 and 8 reduced disease activity in patients with cutaneous lupus erythematosus (CLE) or systemic lupus erythematosus (SLE) with active lupus rash.

Description Chilblain lupus erythematosus (CHLE) or Perniosis is a rare and chronic form of lupus involving the toes, fingers, nose, and ears precipitated by cold exposure. The prevalence is 3–20%, ...

The immune system is the body’s natural defense against disease. In lupus, the immune system creates antibodies that attack the body’s own tissues and organs. The two most common types of lupus are ...

Skin conditions associated with lupus can be significant and play a major role in both the diagnosis of lupus and its clinical course. Of the 11 criteria set by the American College of Rheumatology in ...

6 Nakazono S, Nojima K, Kumagai J, et al. Amicrobial pustulosis-like rash associated with systemic lupus erythematosus. J Dermatol. 2014;41:359–60. doi: 10.1111/1346-8138.12423 7 Gheisari M, Baghani M ...

This woman in her early 30s with an 11 year history of systemic lupus erythematosus (SLE) experienced a sudden disease flare-up with symptoms of SLE encephalopathy. She was treated with ...