Critical to this strategy and its general application is the tactical development of N-aryl trifluoromethyl sulfonamide Brønsted acid donors ... aryl sulfonamides of varying acid strength and ...

Utilizing a high-throughput screening campaign and subsequent structure-guided design, we identify small-molecule inhibitors of this interaction with potent in vitro binding affinity and report ...

The tragic incidents of mass poisoning that occurred when sulfanilamide was formulated into an elixir ... Computational modeling and simulation, applied in structure-based drug design and medical ...

Using advanced electron crystallography techniques, researchers at Stockholm University have succeeded in determining the ...

Using advanced electron crystallography techniques, researchers at Stockholm University have succeeded in determining the ...

This visualization brings Webb's iconic image to life—helping us imagine the true, three-dimensional structure of the universe… and our place within it. Credit: James Webb Space Telescope ...

Working more than 52 hours a week may alter the structure of your brain, new research has found. Being "overworked" could affect the part of the brain linked with problem-solving and memory ...

Researchers led by Université de Montréal pathology and cell-biology professor Marc Therrien have identified major structural ...

“And now that we have this structure, perhaps we can find ways to modulate its function.” For example, compounds that target the receptor could alter how natural sugars are sensed by taste ...

Long working hours might not just be bad for you, they could also be altering the structure of your brain, a new study suggests. The research was conducted by two scientists at South Korea’s ...

Long working hours may alter the structure of the brain, particularly the areas associated with emotional regulation and executive function, such as working memory and problem solving, suggest the ...

Amazon's new pay model rewards top performers, cuts first-time achievers The revised structure places greater emphasis on an employee's rating history rather than just current performance.