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The partners will use UNP's AI-based macrocycle discovery platform to develop synthetic peptide therapeutics for multiple disease targets.
The peptides AM1 and Lac21E self-organize into switchable films at an air–water interface. In an earlier study, it was proposed that both AM1 and Lac21E formed monolayers of α-helical peptides based ...
Cyclic cidofovir (2) displays decreased nephrotoxicity compared to 1, while also exhibiting potent antiviral activity. Here we describe in detail the synthesis and evaluation as prodrugs of four ...
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