Researchers from the Göttingen Cluster of Excellence Multiscale Bioimaging (MBExC) have uncovered the 3D structure of the ...

"This new structure provides clues about which important ... to act as a DNA replication gatekeeper and to the survival of cancer cells. "This work and our structure-activity knowledge gained ...

But filopodia can also wreak havoc: metastatic cancer cells use them to invade new regions of the body. Filopodia are ...

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This three-protein assembly, called the SHOC2-MRAS-PP1C ("SMP") complex, regulates the RAS signaling pathway and helps cancer cells with RAS mutations survive. The high-resolution structure of ...

Cancer cells seldom start off stealthy ... named after the enigmatic Sphinx of Greek lore because of their puzzling structure and function. Two centuries later, sphingolipids are less of a ...

Inside almost every cell in your body is a structure called the nucleus ... This can mean that they have an increase in their risk of cancer. It is usual for cells to repair faults in their genes.

Switching from nanofibres in the blood to virus-like particles in a tumour environment brings drugs to where they are needed ...

It aids the progression and survival of cancer cells through chemoresistance and ... "We used cryo-EM to capture the structure of this transporter and discover how it moves S1P to the outside ...

Left: the three-dimensional structure of a PNMA2 complex ... “This protein normally is only expressed in the brain, in neurons,” Xu says, “but some cancer cells can express it, which can trigger an ...

In our previous work, we found that T cells become dysfunctional with dramatically altered genetic structure within five days of encountering cancer cells in mice. We had originally decided to ...