On day 1, GLP-1 was infused to stimulate endogenous insulin release and suppress endogenous glucagon. On days 2–5, pancreatic endocrine clamps were performed using somatostatin infusions of ...

Diameters of islets and area of insulin- and glucagon-labeled cells within islets on each section were measured with the aid of image analysis software (ImageJ). Numbers of islets, defined as ...

Supplemental BLA accepted for review Paltusotine (Crinetics Pharmaceuticals) Somatostatin receptor type ... types 1 and 2 inhibitor As an adjunct to insulin therapy for glycemic control in adults ...

Somatostatin receptor type 2 agonist Treatment and long-term maintenance of acromegaly in adults. NDA accepted for review Zynquista (Lexicon Pharmaceuticals) Dual sodium-glucose co-transporter types 1 ...

Glucagon is a hormone produced by α cells in the pancreas. It works alongside insulin to regulate blood sugar levels, raising them when they drop too low. However, in people with type 2 diabetes ...

Traditionally, blood sugar regulation has been attributed to the hormones insulin and glucagon, both produced by the pancreas. Insulin lowers blood glucose by promoting its uptake into cells ...

Use of a sodium-glucose cotransporter 2, or SGLT2, inhibitor combined with calorie restriction resulted in greater rates of type 2 diabetes remission compared with calorie restriction alone, according ...

Minnesota Attorney General Keith Ellison on Monday announced a settlement in a lawsuit against insulin manufacturer Novo Nordisk. Minnesota residents will now be able to get Novo Nordisk insulin ...

Many drugs, including insulin, essentially became free. But the American Rescue Plan made a major change that hit drug companies with even larger penalties for raising prices. In January 2024 ...

People who use insulin or sulfonylurea medications to manage blood sugar should consider having a glucagon emergency kit on hand at all times. It’s a nasal spray or injection that treats severe ...

Insulin allows cells to absorb and use glucose. In people with insulin resistance, the cells are unable to use insulin effectively. Insulin resistance occurs when cells in the body do not respond ...