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Experts explain the science on supplements to help you determine which are worth your money—and which are just hype.

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These popular dietary and herbal supplements can be toxic in high doses, cause serious side effects, or interact with medications, doctors warn.

“Fat-soluble vitamins in particular are prone to cause toxicity, as they ‘stick around’ for longer in the body,” says Moutafis. These include vitamins A, D, E, and K.