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The development of oral dosage forms for clinical trials presents a unique set of challenges, particularly in early phases of ...
Thanks to its moderate solubility range, its composition can be changed, and it can be alloyed with other elements to alter both mechanical and shape memory properties. The nickel-titanium alloy ...
With the emergence of PVA-based HME excipients, the typical processing range can even be extended to process temperatures of up to 250 °C. “This way, even high-melting-point APIs can be processed via ...
Solubility, polymorphism, crystallinity, and crystal habit of acetaminophen and racemic (+/-)-ibuprofen were determined by initial screening of 23 solvents for scale-up. Solubility curves were ...