While the allyloxycarbonyl (Alloc) protecting group has played a key role in solid-phase peptide synthesis (SPPS), providing access to a wide range of peptides, its removal has suffered from relying ...

By: Charlie Sternberg Snapdragon Chemistry, a Cambrex company, has successfully developed a new liquid-phase peptide synthesis (LPPS) technology that utilizes traditional active pharmaceutical ...

The LPPS technology supports peptides up to 12 residues long, while larger peptides are then assembled in liquid phase, using a convergent fragment coupling approach. Processes developed with ...

Amide says its automated fast-flow peptide synthesis method bridges the gap between traditional solid phase peptide synthesis and biological expression, allowing production of very long or complex ...

This book provides a practical guide to solid-phase peptide synthesis, covering techniques and methodologies for researchers and students in the field of biochemistry.

CordenPharma Inaugurates Increased Peptide Production of the Largest Worldwide SPPS Manufacturing Plant to Meet Growing Market Demand (Source: CordenPharma) With decades of proven SPPS production, ...

Solid phase peptide synthesis (SPPS) is a technique for peptide synthesis. It can be defined as a process in which a peptide anchored by its C-terminus to an insoluble polymer is assembled by the ...

The polypeptide, on the other hand, was assembled by Fmoc solid phase peptide synthesis on Rink Amide resin. Acylation of the N-terminal amino acid was performed on resin-bound BBN [7–14] using 11 ...

Circular dichroism data were recorded using a JASCO J-820 spectropolarimeter (JASCO Corp., Ltd). General Procedures for the Fmoc Solid-Phase Peptide Synthesis Peptides were synthesized with Fmoc solid ...