A research team at The University of Tokyo has discovered that inhalational anesthetics activate a protein called type 1 ryanodine receptor (RyR1), ...

A team of researchers, led by Professor Chae Un Kim from the Department of Physics at UNIST, has successfully tracked the catalytic pathway of carbonic anhydrase II (CAII), an enzyme that converts ...

In gaseous chlorine or sodium hypochlorite solution (NaClO) there is the formation of hypochlorous acid and hypochlorite ion, in aqueous solutions, which present disinfectant action on microorganisms ...

OBJECTIVE: The purpose of this study was to evaluate the action of sodium hypochlorite (NaOCl) associated with an intracanal medication against Candida albicans and Enterococcus faecalis inoculated in ...

Activation of the sodium-hydrogen exchanger in the heart and vasculature (NHE1 isoform) and the kidneys (NHE3 isoform) may serve as a common mechanism that links both disorders and may underlie their ...

† Key Laboratory of Colloid and Interface Science, Beijing National Laboratory for Molecular Sciences (BNLMS), Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, People’s Republic of ...

The group emphasized balancing survival benefits with toxicity and selecting therapies with distinct mechanisms of action instead of rechallenging patients with similar therapies. What are the goals ...

Cardiac Ca2+/Na+ exchange is mediated by the NCX1 antiporter, whose activity is tightly regulated. This important manuscript describes the structural basis of activation by the lipid DiC8-PIP2 and ...

† Diseases of the Developing World, Tres Cantos Medicines Development Campus, GlaxoSmithKline, c/Severo Ochoa, 2, 28760, Tres Cantos, Madrid, Spain ‡ Robert Robinson Laboratories, Department of ...

RIM’s developers propose a mechanism of action based on nonconscious processes like emotional processing and body awareness. Two Minds Theory (TMT) is a health behavior model that suggests coping ...

How sKl exerts these pleiotropic functions is poorly understood. One hurdle in understanding sKl’s mechanism of action as a “hormone” has been the inability to identify a receptor that mediates its ...